Analysis of folding intermediates from the main toxin of Naja naja samarensis containing two blocked cysteines
نویسندگان
چکیده
منابع مشابه
Reoxidation and renaturation studies on the main toxin of Naja naja samarensis.
The main toxin of Naja naja samarensis is a very small and rigid protein (Mr 6850, 8 cysteines). When fully reduced, it regains its native conformation by a mechanism involving a rapid cysteine oxidation and a slower, less temperature-dependent disulfide exchange. In a native-like form of the protein we observed a population whose cysteines were incompletely reoxidized. When intermediates with ...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1986
ISSN: 0014-5793
DOI: 10.1016/0014-5793(86)80528-2